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Investigation of the action of poly(ADP-ribose)-synthesising enzymes on NAD+ analogues

ADP-ribosyl transferases with diphtheria toxin homology (ARTDs) catalyse the covalent addition of ADP-ribose onto different acceptors forming mono- or poly(ADP-ribos)ylated proteins. Out of the 18 members identified, only four are known to synthesise the complex poly(ADP-ribose) biopolymer. The inve...

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Detalles Bibliográficos
Principais autores: Sarah Wallrodt, Edward L. Simpson, Andreas Marx
Formato: Artigo
Idioma:Inglês
Publicado: Beilstein-Institut 2017-03-01
Series:Beilstein Journal of Organic Chemistry
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Acceso en liña:https://doi.org/10.3762/bjoc.13.49
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