Impact of diabetes mellitus on treatment efficacy in patients with advanced pancreatic cancer: the Italian, multicenter, observational PANCAKE study

Background: Diabetes mellitus (DM) is a known risk factor for pancreatic ductal adenocarcinoma (PDAC). Preclinical evidence suggests higher glucose levels may enhance chemotherapy injury to PDAC cells. Clinical evidence of DM’s impact in patients with PDAC receiving palliative treatment remains conf...

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Bibliografiska uppgifter

Huvudupphov:	P. Andena, G. Tine, F. Nichetti, A. Pretta, L. Bartalini, S. Ljevar, A. Michelotti, L. Salvatore, M. Prisciandaro, A. Franza, G. Grelli, P. Ziranu, M. Bensi, V. Mazzaferro, J. Coppa, C. Sciortino, G. Zapelloni, C. Pircher, S.K. Garattini, C. Vivaldi, G. Tortora, M. Scartozzi, F. de Braud, F. Pietrantonio, R. Miceli, M. Niger
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2026-03-01
Serie:	ESMO Gastrointestinal Oncology
Ämnen:	pancreatic cancer diabetes glycemia chemotherapy Bayesian joint modelling
Länkar:	http://www.sciencedirect.com/science/article/pii/S2949819825001451
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