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Plasma proteome in LGI-1 autoimmune encephalitis

Abstract Background Leucine-rich glioma-inactivated antibody associated autoimmune encephalitis (LGI-1 AE) is a rare immune mediated neuroinflammatory disease resulting in seizures and cognitive impairment. LGI-1 AE can respond well to immunotherapy, however residual symptoms, particularly cognitive...

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Autors principals: Robb Wesselingh, Nabil Seery, Katherine Ko, Sarah Griffith, Christina Kazzi, William T. O’Brien, Lauren Giesler, Tiffany Rushen, Liora ter Horst, Amy Halliday, Mirasol Forcadela, Tracie Tan, Genevieve Skinner, Hannah Ford, Katherine Buzzard, Andrew Duncan, Wendyl D’Souza, Stuart McDonald, Tomas Kalincik, Udaya Seneviratne, Richard Macdonell, David Gillis, Sudarshini Ramanathan, Stephen W. Reddel, Stefan Blum, Todd A. Hardy, Charles Malpas, Terence J. O’Brien, Paul Sanfilippo, Helmut Butzkueven, Mastura Monif, the Australian Autoimmune Encephalitis Consortium
Format: Artigo
Idioma:Inglês
Publicat: BMC 2026-05-01
Col·lecció:Journal of Neuroinflammation
Matèries:
Autoimmune encephalitis
LGI-1
Biomarkers
Proteomics
Transcriptomics
IL-6
Accés en línia:https://doi.org/10.1186/s12974-026-03851-x
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