Is Increased Intracellular Calcium in Red Blood Cells a Common Component in the Molecular Mechanism Causing Anemia?

For many hereditary disorders, although the underlying genetic mutation may be known, the molecular mechanism leading to hemolytic anemia is still unclear and needs further investigation. Previous studies revealed an increased intracellular Ca2+ in red blood cells (RBCs) from patients with sickle ce...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Laura Hertz, Rick Huisjes, Esther Llaudet-Planas, Polina Petkova-Kirova, Asya Makhro, Jens G. Danielczok, Stephane Egee, Maria del Mar Mañú-Pereira, Richard van Wijk, Joan-Lluis Vives Corrons, Anna Bogdanova, Lars Kaestner
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2017-09-01
Schriftenreihe:	Frontiers in Physiology
Schlagworte:	rare anemia erythrocyte calcium homeostasis channelopathies live cell imaging spherocytosis
Online-Zugang:	http://journal.frontiersin.org/article/10.3389/fphys.2017.00673/full
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