The effect of dissolution medium, rotation speed and compaction pressure on the intrinsic dissolution rate of amlodipine besylate, using the rotating disk method

The aim of this study was to evaluate the effect of dissolution medium, rotation speed and compaction pressure on the intrinsic dissolution rate (IDR) of the antihypertensive drug amlodipine besylate, using the rotating disk method. Accordingly, a fractional factorial design (33-1) was used, employi...

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Autores principales:	Leandro Giorgetti, Michele Georges Issa, Humberto Gomes Ferraz
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2014-09-01
Colección:	Brazilian Journal of Pharmaceutical Sciences
Materias:	Besilato de anlodipino/dissolução intrínseca Sistema de classificação biofarmacêutica Fármacos/delineamento experimental Fármacos/anti-hipertensivos/ Besilato de anlodipino
Acceso en línea:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300513&lng=en&tlng=en
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