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The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses

Host proteins sense viral products and induce defence mechanisms, particularly in immune cells. Using cell-free assays and quantitative mass spectrometry, we determined the interactome of capsid-host protein complexes of herpes simplex virus and identified the large dynamin-like GTPase myxovirus res...

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Hlavní autoři: Manutea C Serrero, Virginie Girault, Sebastian Weigang, Todd M Greco, Ana Ramos-Nascimento, Fenja Anderson, Antonio Piras, Ana Hickford Martinez, Jonny Hertzog, Anne Binz, Anja Pohlmann, Ute Prank, Jan Rehwinkel, Rudolf Bauerfeind, Ileana M Cristea, Andreas Pichlmair, Georg Kochs, Beate Sodeik
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications Ltd 2022-04-01
Edice:eLife
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On-line přístup:https://elifesciences.org/articles/76804
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