Neuron-Specific Glycine Metabolism Links Transfer RNA Epitranscriptomic Regulation to Complex Behaviors

Background: The presence of treatment resistance in neuropsychiatric disease suggests that novel mechanism-based discoveries and therapies could benefit the field, with a viable candidate being transfer RNA (tRNA) epitranscriptomics. Nsun2 tRNA methyltransferase depletion in mature neurons elicits c...

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Bibliografische gegevens

Hoofdauteurs:	Jennifer Blaze, Viviana Dolores Evans, Jessica Abigail Feria Pliego, Petr Unichenko, Behnam Javidfar, Soeren Heissel, Hanan Alwaseem, Zachary Pennington, Denise Cai, Henrik Molina, Christian Henneberger, Schahram Akbarian
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2025-03-01
Reeks:	Biological Psychiatry Global Open Science
Onderwerpen:	Cell metabolism Epitranscriptome Glycine Neuropsychiatric tRNAs
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2667174324001459
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