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IgM has a better relative distribution in inflammation sites and tumor tissues than IgG

Abstract Immunoglobulins (Igs) play a crucial role in host’s defense and in developing therapies against inflammatory diseases and cancer. Herein, we first studied the relative distribution of IgM and IgG in mouse models with acute or chronic inflammation. We found that IgM showed a more selective d...

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Principais autores: Abdulaziz M. Aldayel, Mohammad Bosaeed, Sarah Almansour, Naif Khalaf Alharbi, Mohammed Alenazi, Haya A. Aljami, Omar Aldibasi, Abdulrhman Aljouie, Haiyue Xu, Zhengrong Cui
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-03-01
Serier:Journal of Nanobiotechnology
Fag:
Antibodies
Nanoparticle size
Distribution
Inflammation
Tumor
Online adgang:https://doi.org/10.1186/s12951-025-03213-4
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