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A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function

Abstract Post-translational modifications, such as lysine acetylation, regulate the activity of diverse proteins across many cellular compartments. Protein deacetylation in mitochondria is catalyzed by the enzymatic activity of the NAD+-dependent deacetylase sirtuin 3 (SIRT3), however it remains unc...

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Principais autores: Rachid Boutoual, Hyunsun Jo, Indra Heckenbach, Ritesh Tiwari, Herbert Kasler, Chad A. Lerner, Samah Shah, Birgit Schilling, Vincenzo Calvanese, Matthew J. Rardin, Morten Scheibye-Knudsen, Eric Verdin
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2022-08-01
סדרה:Scientific Reports
גישה מקוונת:https://doi.org/10.1038/s41598-022-18114-x
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