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Comet assay to measure DNA repair: approach and applications.

Cellular repair enzymes remove virtually all DNA damage before it is fixed; repair therefore plays a crucial role in preventing cancer. Repair studied at the level of transcription correlates poorly with enzyme activity, and so assays of phenotype are needed. In a biochemical approach, substrate nuc...

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Auteurs principaux: Amaya eAzqueta, Jana eSlyskova, Sabine A.S. Langie, Isabel O'Neill Gaivão, Andrew R. Collins
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2014-08-01
Collection:Frontiers in Genetics
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Accès en ligne:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00288/full
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