Attenuated crosstalk between urothelium and fibroblasts promotes ureteral stricture development

BackgroundUreteral stricture (US), characterized by fibrotic remodeling of the ureteral wall, represents an obstructive urological disorder with incompletely characterized pathophysiological mechanisms. This study integrates single-cell RNA sequencing (scRNA-seq) with immunohistochemical validation...

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Autores principales:	Rongchang Guo, Xuhong Zhang, Chengbang Wang, Junqi Cui, Kai Wang, Bao Hua, Shangqing Song, Yun Zou, Lin Zhou, Haisong Tan, Siyuan Liang, Le Tao, Jiangyi Wang, Wenfeng Li, Long Li, Guopeng Yu, Qing Yang, Yushan Liu, Bin Xu, Yiwei Wang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-03-01
Colección:	Frontiers in Immunology
Materias:	fibroblast single-cell RNA sequencing ureter ureteral stricture urothelium
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1786116/full
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