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Epistasis, core-genome disharmony, and adaptation in recombining bacteria

ABSTRACT Recombination of short DNA fragments via horizontal gene transfer (HGT) can introduce beneficial alleles, create genomic disharmony through negative epistasis, and create adaptive gene combinations through positive epistasis. For non-core (accessory) genes, the negative epistatic cost is li...

Deskribapen osoa

Gorde:
Egile Nagusiak: Aidan J. Taylor, Koji Yahara, Ben Pascoe, Seungwon Ko, Leonardos Mageiros, Evangelos Mourkas, Jessica K. Calland, Santeri Puranen, Matthew D. Hitchings, Keith A. Jolley, Carolin M. Kobras, Sion Bayliss, Nicola J. Williams, Arnoud H. M. van Vliet, Julian Parkhill, Martin C. J. Maiden, Jukka Corander, Laurence D. Hurst, Daniel Falush, Paul Keim, Xavier Didelot, David J. Kelly, Samuel K. Sheppard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2024-06-01
Saila:mBio
Gaiak:
Campylobacter
hybridization
epistasis
introgression
horizontal gene transfer
recombination
Sarrera elektronikoa:https://journals.asm.org/doi/10.1128/mbio.00581-24
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