Detachment of Hexokinase II From Mitochondria Promotes Collateral Sensitivity in Multidrug Resistant Chronic Myeloid Leukemia Cells

Chronic Myeloid Leukemia is a neoplastic disease characterized by the abnormal expansion of hematopoietic cells with compromised functions. Leukemic cells often display a multidrug resistance phenotype, enabling them to evade a number of structurally unrelated cytotoxic compounds. One of those mecha...

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Autori principali:	Thaís Oliveira, Douglas Lemos, Louise Jean, Jéssica M. Kawashima, Vitória R. de Azevedo, Eduardo J. Salustiano, Vivian M. Rumjanek, Robson Q. Monteiro
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-05-01
Serie:	Frontiers in Oncology
Soggetti:	hexokinase II glutathione chemoresistance chronic myelogenous leukemia metabolism
Accesso online:	https://www.frontiersin.org/articles/10.3389/fonc.2022.852985/full
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