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Short-Chain Fatty Acids Weaken Ox-LDL-Induced Cell Inflammatory Injury by Inhibiting the NLRP3/Caspase-1 Pathway and Affecting Cellular Metabolism in THP-1 Cells

Short-chain fatty acids (SCFAs) are important anti-inflammatory metabolites of intestinal flora. Oxidized low-density lipoprotein (ox-LDL)-induced macrophage activation is critical for the formation of atherosclerosis plaque. However, the association between SCFAs and ox-LDL-induced macrophage activ...

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Автори: Chengxue Yi, Wen Sun, Longkun Ding, Man Yan, Chang Sun, Chenguang Qiu, Dongxu Wang, Liang Wu
Формат: Artigo
Мова:Inglês
Опубліковано: MDPI AG 2022-12-01
Серія:Molecules
Предмети:
short chain fatty acids
oxidized low-density lipoprotein
metabolomics
anti-inflammation
cellular metabolism
Онлайн доступ:https://www.mdpi.com/1420-3049/27/24/8801
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