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Inclusion biogenesis and reactivation of persistent Chlamydia trachomatis requires host cell sphingolipid biosynthesis.

Chlamydiae are obligate intracellular pathogens that must coordinate the acquisition of host cell-derived biosynthetic constituents essential for bacterial survival. Purified chlamydiae contain several lipids that are typically found in eukaryotes, implying the translocation of host cell lipids to t...

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Autori principali: D Kesley Robertson, Ling Gu, Regina K Rowe, Wandy L Beatty
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2009-11-01
Serie:PLoS Pathogens
Accesso online:http://europepmc.org/articles/PMC2774160?pdf=render
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