In silico characterization of chromosomally integrated blaCTX-M genes among clinical Enterobacteriaceae in Africa: insights from whole-genome analysis

Antimicrobial resistance (AMR) mediated by extended-spectrum β-lactamases (ESBLs) is a growing global concern, particularly among Enterobacteriaceae. The CTX-M-type ESBLs, encoded by the blaCTX-M gene, are of significant public health importance due to their high prevalence and broad geographic dist...

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Autores principales:	Misheck Shawa, Herman Chambaro, Harvey K. Kamboyi, Clement Sulwe, Joseph Y. Chizimu, Situmbeko J. Nasilele, Shohei Ogata, Mulemba Samutela, Tuvshinzaya Zorigt, Steward Mudenda, Manyando Simbotwe, Mwamba Nsofwa, Jedidiah Chanda, Freeman Chabala, Mike Nundwe, Joseph Ndebe, Msangwa Sinjani, Kyoko Hayashida, Naganori Nao, Roma Chilengi, Hirofumi Sawa, Yasuhiko Suzuki, Bernard Hang'ombe, Masahiro Kajihara, Hideaki Higashi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2025-09-01
Colección:	Frontiers in Microbiology
Materias:	blaCTX-M Enterobacteriaceae Africa chromosomal ISEcp1 IS26
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1655907/full
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