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Angiotensin II is a new component involved in splenic T lymphocyte responses during Plasmodium berghei ANKA infection.

The contribution of T cells in severe malaria pathogenesis has been described. Here, we provide evidence for the potential role of angiotensin II (Ang II) in modulating splenic T cell responses in a rodent model of cerebral malaria. T cell activation induced by infection, determined by 3 to 4-fold e...

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Autors principals: João Luiz Silva-Filho, Mariana Conceição Souza, Claudio Teixeira Ferreira-Dasilva, Leandro Souza Silva, Maria Fernanda Souza Costa, Tatiana Almeida Padua, Maria das Graças Henriques, Alexandre Morrot, Wilson Savino, Celso Caruso-Neves, Ana Acacia Sá Pinheiro
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3639972?pdf=render
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