Metformin attenuates diabetes-induced osteopenia in rats is associated with down-regulation of the RAGE-JAK2-STAT1 signal axis

Background: Osteopenia and fragile fractures are diabetes-associated complications. Many hypoglycemic drugs have effects on bone metabolism. Metformin, as is a prescribed medication for type 2 diabetes mellitus (T2DM), had been reported to have osteoprotective effects beyond its hypoglycemic effect,...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Rui Lin, Bilian Xu, Zhiqiang Ye, Yin Gao, Haiping Fang, Jintong Song, Dahong Liang, Lingna Liu, Zilong Hu, Min Zhang, Jinsong Wei, Feifu Deng, Xiangxin Zhong, Liao Cui, Yanzhi Liu
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2023-05-01
Serija:	Journal of Orthopaedic Translation
Teme:	Diabetes Bone Osteoporosis Osteopenia Metformin Fragility
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2214031X23000293
Oznake:	Označite Brez oznak, prvi označite!