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Tunable Drug Release Rate Using Modular Oral Dosage Forms

Oral dosage forms with adjustable drug release profiles were prepared using progesterone (PGR) as a poorly-soluble model drug. The dosage forms were made as stack assemblies of functional modules. The modules were made as PGR-carrying HPMC films cut into wafer-like circular pieces. Two types of modu...

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Principais autores: Mario A. Cano-Vega, Laura M. Arango-Salazar, Rodolfo Pinal
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-07-01
Serier:Pharmaceutics
Fag:
solubility
pharmaceutical films
drug release kinetics
controlled release
modular dosage forms
spring-parachute
Online adgang:https://www.mdpi.com/1999-4923/15/7/1905
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