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A retrospective study of the impact of comorbidity, polypharmacy and demographic factors on patient inclusion and healthcare delivery in phase I oncology trials

Abstract Background Phase I trials include patients with metastatic cancer and complex health conditions. Understanding baseline comorbidity and demographic features is critical to improving trial design. Methods We used electronic patient records to study the association of comorbidity, polypharmac...

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Bibliografiske detaljer
Principais autores: Hoda Nemat, Martin Orr, Lucy Barrow, Bindu Raobaikady, Sheila Matharu, Lisa Scerri, Udai Banerji, Ceire Costelloe
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-08-01
Serier:BJC Reports
Online adgang:https://doi.org/10.1038/s44276-025-00165-y
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