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Roads to Stat3 Paved with Cadherins

The engagement of cadherins, cell-to-cell adhesion proteins, triggers a dramatic increase in the levels and activity of the Rac/Cdc42 GTPases, through the inhibition of proteasomal degradation. This leads to an increase in transcription and secretion of IL6 family cytokines, activation of their comm...

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Autors principals: Hanad Adan, Juliet Daniel, Leda Raptis
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-08-01
Col·lecció:Cells
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Accés en línia:https://www.mdpi.com/2073-4409/11/16/2537
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