How Does Our Knowledge on the Na+/H+ Exchanger NHE1 Obtained by Biochemical and Molecular Analyses Keep up With Its Recent Structure Determination?

Na+/H+ exchangers are membrane transporters conserved in all living systems and therefore are assumed to be amongst the most ancestral molecular devices that equipped the first protocells. Following the cloning and sequencing of its gene, the mammalian NHE1, that regulates pH and volume in all cells...

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Principais autores:	Mallorie Poet, Denis Doyen, Emmanuel Van Obberghen, Gisèle Jarretou, Yann Bouret, Laurent Counillon
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-07-01
Colecção:	Frontiers in Physiology
Assuntos:	Na+/H+ exchanger 1 structure function studies allosteric regulation kinetics protein 3D structure
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphys.2022.907587/full
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