Burn‐Induced Gut Microbiota Dysbiosis Aggravates Skeletal Muscle Atrophy by Tryptophan‐Kynurenine Mediated AHR Pathway Activation

Abstract The hypermetabolic response associated with burns is characterized by skeletal muscle atrophy and an increased incidence of disability and death. Significant remodeling of the gut microbiota occurs after severe burn trauma. However, the specific mechanisms by which gut microbiota contribute...

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Detalhes bibliográficos

Principais autores:	Shan Gao, Yan Leng, Zhen Qiu, Kai Li, Jun Li, Jian Peng, Weiguo Xie, Shaoqing Lei, Zhongyuan Xia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-04-01
coleção:	Advanced Science
Assuntos:	burn injury gut microbiota gut‐muscle axis skeletal muscle atrophy tryptophan
Acesso em linha:	https://doi.org/10.1002/advs.202409296
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