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Inhibitory mechanisms of decoy receptor 3 in cecal ligation and puncture-induced sepsis

ABSTRACT Despite its high mortality, specific and effective drugs for sepsis are lacking. Decoy receptor 3 (DcR3) is a potential biomarker for the progression of inflammatory diseases. The recombinant human DcR3-Fc chimera protein (DcR3.Fc) suppresses inflammatory responses in mice with sepsis, whic...

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Main Authors: Jingqian Su, Wenzhi Chen, Fen Zhou, Rui Li, Zhiyong Tong, Shun Wu, Zhen Ye, Yichao Zhang, Ben Lin, Xing Yu, Biyun Guan, Zhihua Feng, Kunsen Chen, Qi Chen, Long Chen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2024-06-01
Series:mBio
Subjects:
gut microbiota
decoy receptor 3
sepsis
anti-inflammatory
Online Access:https://journals.asm.org/doi/10.1128/mbio.00521-24
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