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DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress

Abstract Inter-organelle contact and communication between mitochondria and sarco/endoplasmic reticulum (SR/ER) maintain cellular homeostasis and are profoundly disturbed during tissue ischemia. We tested the hypothesis that the formin Diaphanous-1 (DIAPH1), which regulates actin dynamics, signal tr...

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Príomhchruthaitheoirí: Gautham Yepuri, Lisa M. Ramirez, Gregory G. Theophall, Sergei V. Reverdatto, Nosirudeen Quadri, Syed Nurul Hasan, Lei Bu, Devi Thiagarajan, Robin Wilson, Raquel López Díez, Paul F. Gugger, Kaamashri Mangar, Navneet Narula, Stuart D. Katz, Boyan Zhou, Huilin Li, Aleksandr B. Stotland, Roberta A. Gottlieb, Ann Marie Schmidt, Alexander Shekhtman, Ravichandran Ramasamy
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2023-10-01
Sraith:Nature Communications
Rochtain ar líne:https://doi.org/10.1038/s41467-023-42521-x
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