Sex-specific proximal tubular cell differentiation pathways identified by single-nucleus RNA sequencing

Abstract Postnatal kidney growth is substantial and involves expansion in kidney tubules without growth of new nephrons, which are the functional units of the kidney. Proliferation and differentiation pathways underpinning nephron elongation are not well defined. To address this, we performed sequen...

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Detalhes bibliográficos

Principais autores:	Yueh-An Lu, Tanya Smith, Sumukh Deshpande, Chia-Te Liao, Bnar Talabani, Irina Grigorieva, Anna Mason, Robert Andrews, Timothy Bowen, Philip R. Taylor, Donald Fraser
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-10-01
coleção:	Scientific Reports
Assuntos:	Cell biology and structure Chronic kidney disease Epithelial Kidney tubule MRNA Proximal tubule
Acesso em linha:	https://doi.org/10.1038/s41598-024-73102-7
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