Myeloid GHSR Deficiency Protects Against Thermogenic Impairment in Aging Through Immune Remodeling of Brown Adipose Tissue

Thermoregulatory dysfunction is a major pathophysiological consequence of aging, affecting many elderly individuals. Growth hormone secretagogue receptor (GHSR) regulates energy homeostasis and immune function. We previously showed that global GHSR deletion improves thermogenic adaptation of brown a...

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Detalhes bibliográficos

Principais autores:	Hye Won Han, Da Mi Kim, Reza Baratiboldaji, Hongying Wang, Zeyu Liu, Zheng Shen, Deepak K. Jha, Tadesse Teferra, Endang M. Septiningsih, Bhimanagouda Patil, Yuxiang Sun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-02-01
Colecção:	Cells
Assuntos:	ghrelin growth hormone secretagogue receptor (GHSR) aging thermogenesis inflammation macrophages
Acesso em linha:	https://www.mdpi.com/2073-4409/15/4/321
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