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Clump sequencing exposes the spatial expression programs of intestinal secretory cells

Combining scRNA-seq with spatial information to enable the reconstruction of spatially-resolved cell atlases is challenging for rare cell types. Here the authors present ClumpSeq, an approach for sequencing small clumps of tissue attached cells, and apply it to establish spatial atlases for all secr...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Rita Manco, Inna Averbukh, Ziv Porat, Keren Bahar Halpern, Ido Amit, Shalev Itzkovitz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2021-05-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-021-23245-2
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