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EGFR Signaling and Related Pathways: Potential Targets for CRISPR‐Mediated Gene Editing System in the Colorectal Cancer

ABSTRACT As the original member of the huge family of growth factor receptors, the epidermal growth factor receptor (EGFR) has shown inherent tyrosine kinase activity. In addition to its prototypic ligand, EGF, it is activated by TGF‐α. EGFR and its ligand contribute to the pathogenesis of colorecta...

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Главные авторы: Mobina Tabibian, Solat Eslami, Soudeh Ghafouri‐Fard
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley 2025-12-01
Серии:Computational and Systems Oncology
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Online-ссылка:https://doi.org/10.1002/cso2.70008
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