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Therapeutic Efficacy of Interferon-Gamma and Hypoxia-Primed Mesenchymal Stromal Cells and Their Extracellular Vesicles: Underlying Mechanisms and Potentials in Clinical Translation

Multipotent mesenchymal stromal cells (MSCs) hold promises for cell therapy and tissue engineering due to their self-renewal and differentiation abilities, along with immunomodulatory properties and trophic factor secretion. Extracellular vesicles (EVs) from MSCs offer similar therapeutic effects. H...

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Principais autores: Yu Ling Tan, Maimonah Eissa Al-Masawa, Sue Ping Eng, Mohamad Nasir Shafiee, Jia Xian Law, Min Hwei Ng
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-06-01
Serier:Biomedicines
Fag:
mesenchymal stromal cells
extracellular vesicles
priming
interferon-gamma
hypoxia
pre-clinical
Online adgang:https://www.mdpi.com/2227-9059/12/6/1369
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