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The profile and prognostic significance of bone marrow T-cell differentiation subsets in adult AML at diagnosis

BackgroundT lymphocytes in tumor microenvironment play a pivotal role in the anti-tumor immunity, and the memory of T cells contributes to the long-term protection against tumor antigens. Compared to solid tumors, studies focusing on the T-cell differentiation in the acute myeloid leukemia (AML) bon...

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Main Authors: Kai Sun, Zong-Yan Shi, Ya-Zhe Wang, Dai-Hong Xie, Yan-Rong Liu, Qian Jiang, Hao Jiang, Xiao-Jun Huang, Ya-Zhen Qin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Immunology
Subjects:
AML
memory T cell
naive T cell
DNMT3A mutation
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1418792/full
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