Experimental and Computational Structural Studies of 2,3,5-Trisubstituted and 1,2,3,5-Tetrasubstituted Indoles as Non-Competitive Antagonists of GluK1/GluK2 Receptors

The blockade of kainate receptors, in particular with non-competitive antagonists, has—due to their anticonvulsant and neuroprotective properties—therapeutic potential in many central nervous system (CNS) diseases. Deciphering the structural properties of kainate receptor ligands is crucial to desig...

Descripció completa

Dades bibliogràfiques

Autors principals:	Agata Bartyzel, Agnieszka A. Kaczor, Ghodrat Mahmoudi, Ardavan Masoudiasl, Tomasz M. Wróbel, Monika Pitucha, Dariusz Matosiuk
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-04-01
Col·lecció:	Molecules
Matèries:	indole derivatives kainate receptor ligands quantum chemical calculations X-ray studies
Accés en línia:	https://www.mdpi.com/1420-3049/27/8/2479
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!