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AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells.

<h4>Background</h4>Lung cancer is the leading cause of cancer-related deaths worldwide, so research and development of potential therapeutic targets is urgent.<h4>Methods</h4>The target gene, AKR1C2, was screened using the TCGA and FerrDb databases. The expression of AKR1C2 in lung cancer, its corre...

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Autori principali: Yi Cui, Zhihui Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2025-01-01
Serie:PLoS ONE
Accesso online:https://doi.org/10.1371/journal.pone.0325995
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