The application of 2-NBDG as a fluorescent tracer for assessing hepatic glucose production in mice during hyperinsulinemic euglycemic clamp

Methods of performing insulin clamps vary between laboratories. Here we present a protocol of insulin clamping in conscious mice, with the significant advantage of avoiding multiple surgical catheterizations and non-physiologic metabolism during the induction of anesthesia. Using this technique we a...

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Автори:	Shuainan Liu, Quan Liu, Sujuan Sun, Qian Jiang, Jun Peng, Zhufang Shen
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2012-08-01
Серія:	Acta Pharmaceutica Sinica B
Предмети:	Conscious mice Hyperinsulinemic euglycemic clamp 2-NBDG Hepatic glucose production
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2211383512000937
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