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Navigating the risks: a systematic review of immune checkpoint inhibitor therapy before liver transplant for hepatocellular carcinoma and its impact on allograft rejection and survival outcomes

BackgroundThe administration of immune checkpoint inhibitors (ICIs) prior to liver transplantation (LT) for hepatocellular carcinoma (HCC) has been reported. Several studies suggest that ICIs may elevate the risk of allograft rejection (AR) and influence other clinical outcomes. This meta-analysis a...

Täydet tiedot

Tallennettuna:
Päätekijät: Donghua Liu, Xinyi Wang, Xuelian Liu, Jing Li
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2025-10-01
Sarja:Frontiers in Oncology
Aiheet:
hepatocellular carcinoma
immune checkpoint inhibitors
liver transplant
allograft rejection
meta-analysis
Linkit:https://www.frontiersin.org/articles/10.3389/fonc.2025.1689820/full
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