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Mitotic catastrophe–related six-gene signature predicts prognosis, tumor immune landscape, and therapeutic response in lung adenocarcinoma

Abstract Background Lung adenocarcinoma (LUAD) exhibits significant molecular and immune heterogeneity, limiting the prognostic and therapeutic value of single biomarkers. Mitotic catastrophe (MC) is a key biological axis, but externally validated MC-related gene (MCRG) signatures integrating immune...

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主要な著者: Minghao Luo, Guoqing Zhu, Weiquan Zhong
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2026-05-01
シリーズ:BMC Medical Genomics
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オンライン・アクセス:https://doi.org/10.1186/s12920-026-02380-z
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