Thematic review series: Lipid Posttranslational Modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids

Glycosylphosphatidylinositol (GPI) anchoring of cell surface proteins is the most complex and metabolically expensive of the lipid posttranslational modifications described to date. The GPI anchor is synthesized via a membrane-bound multistep pathway in the endoplasmic reticulum (ER) requiring >20 g...

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Detalles Bibliográficos

Principais autores:	Orlean Peter, Anant K. Menon
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2007-05-01
Series:	Journal of Lipid Research
Assuntos:	glycosyltransferase flippase dolichol phosphatidylethanolamine phosphatidylinositol endoplasmic reticulum
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0022227520435461
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