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A feedback loop between plakophilin 4 and YAP signaling regulates keratinocyte differentiation

Summary: The Hippo signaling pathway is an important regulator of organ growth and differentiation, and its deregulation contributes to the development of cancer. The activity of its downstream targets YAP/TAZ depends on adherens junctions. Plakophilin 4 (PKP4) is a cell-type specific adherens junct...

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書誌詳細
主要な著者: Lisa Müller, Tony Gutschner, Mechthild Hatzfeld
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2024-09-01
シリーズ:iScience
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2589004224019874
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