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Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia.

STAT5 controls essential cellular functions and is encoded by two genes, Stat5a and Stat5b. To provide insight to the mechanisms linking hematologic malignancy to STAT5 activation/regulation of target genes, we identified STAT5 target genes and focused on Dpf3 gene, which encodes for an epigenetic f...

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Autors principals: Marina Theodorou, Matthaios Speletas, Antigoni Mamara, Georgia Papachristopoulou, Vassiliki Lazou, Andreas Scorilas, Eleni Katsantoni
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3796511?pdf=render
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