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Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.

Various therapeutic approaches have been studied for the treatment of Duchenne muscular dystrophy (DMD), but none of these approaches have led to significant long-term effects in patients. One reason for this observed inefficacy may be the use of inappropriate animal models for the testing of therap...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Kelly M Gutpell, William T Hrinivich, Lisa M Hoffman
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2015-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC4301874?pdf=render
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