Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) continue to wreak havoc across the globe. Higher transmissibility and immunologic resistance of VOCs bring unprecedented challenges to epidemic extinguishment. Here we describe a monoclonal antibody, 2G1...

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Autors principals:	Hang Ma, Yingying Guo, Haoneng Tang, Chien-Te K. Tseng, Lei Wang, Huifang Zong, Zhenyu Wang, Yang He, Yunsong Chang, Shusheng Wang, Haiqiu Huang, Yong Ke, Yunsheng Yuan, Mingyuan Wu, Yuanyuan Zhang, Aleksandra Drelich, Kempaiah Rayavara Kempaiah, Bi-Hung Peng, Ailin Wang, Kaiyong Yang, Haiyang Yin, Junjun Liu, Yali Yue, Wenbo Xu, Shuangli Zhu, Tianjiao Ji, Xiaoju Zhang, Ziqi Wang, Gang Li, Guangchun Liu, Jingjing Song, Lingling Mu, ZongShang Xiang, Zhangyi Song, Hua Chen, Yanlin Bian, Baohong Zhang, Hui Chen, Jiawei Zhang, Yunji Liao, Li Zhang, Li Yang, Yi Chen, John Gilly, Xiaodong Xiao, Lei Han, Hua Jiang, Yueqing Xie, Qiang Zhou, Jianwei Zhu
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2022-02-01
Col·lecció:	Cell Discovery
Accés en línia:	https://doi.org/10.1038/s41421-022-00381-7
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