Dual drug-loaded tumor-targeted polymeric nanoparticles for enhancing therapeutic response in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease where standard-of-care chemotherapeutic drugs have limited efficacy due to the development of drug resistance and poor drug delivery caused by a highly desmoplastic tumor microenvironment. Combining multiple drugs in a tumor-targeting carri...

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Principais autores:	Naga Malleswara Rao Nakka, Hari Krishnareddy Rachamala, Ramcharan Singh Angom, Nagamalleswara Rao Indla, Shamit Kumar Dutta, Enfeng Wang, Santanu Bhattacharya, Annadanam V. Sesha Sainath, Hani Babiker, Krishnendu Pal, Debabrata Mukhopadhyay
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-10-01
coleção:	Materials Today Bio
Assuntos:	Pancreatic ductal adenocarcinoma Tumor-targeted therapy Amphiphilic tri-block copolymer Gemcitabine Paclitaxel Polymer nanoparticles
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2590006424002606
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