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Granulocytes affect double-strand break repair assays in primary human lymphocytes.

Patients who develop therapy-related myelodysplasia/acute myeloid leukemia after autologous-hematopoietic stem cell (aHCT) transplant show lower expression levels of DNA repair genes in their pre-aHCT CD34+ cells. To investigate whether this leads to functional differences in DNA repair abilities me...

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Principais autores: Sandrine Lacoste, Ravi Bhatia, Smita Bhatia, Timothy R O'Connor
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2014-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC3965556?pdf=render
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