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Role of carbonic anhydrase IV in the bicarbonate-mediated activation of murine and human sperm.

HCO(3) (-) is the signal for early activation of sperm motility. In vivo, this occurs when sperm come into contact with the HCO(3) (-) containing fluids in the reproductive tract. The activated motility enables sperm to travel the long distance to the ovum. In spermatozoa HCO(3) (-) stimulates the a...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Petra M Wandernoth, Michael Raubuch, Nadja Mannowetz, Holger M Becker, Joachim W Deitmer, William S Sly, Gunther Wennemuth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2010-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC2991337?pdf=render
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