Synthesis and biological evaluation of novel tricyclic matrinic derivatives as potential anti-filovirus agents
Twenty-six novel tricyclic sophoridinic and matrinic derivatives containing a common chlorinated benzene fragment were designed, synthesized and evaluated for their anti-ebolavirus (EBOV) activities. Structureactivity relationship analysis indicated: (i) 12N-dichlorobenzyl motif was beneficial for...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Elsevier
2018-07-01
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| Cyfres: | Acta Pharmaceutica Sinica B |
| Mynediad Ar-lein: | http://www.sciencedirect.com/science/article/pii/S2211383517305130 |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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