Protolytic properties and biological activity of spinorphin and its butyric acid derivatives in aqueous solution

Abstract The present work describes the protolytic properties and in vitro biological activity of spinorphin (Leu-Val-Val-Tyr-Pro-Trp-Thr) and three spinorphin derivatives containing butyric acid residue: Butyryl-Lys-Lys-Leu-Leu-Val-Tyr-Pro-Trp-Thr, Butyryl-Lys-Lys-Leu-Val-Val-Tyr-Pro-Trp-Thr (butyr...

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Autori principali:	Marek Pająk, Elżbieta Kamysz, Marcin Banach, Wojciech Michał Jankowski, Aleksandra Tarasiuk-Zawadzka, Jakub Fichna, Magdalena Woźniczka
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2025-09-01
Serie:	Amino Acids
Soggetti:	Spinorphin Potentiometry Protonation constant Neutral red uptake Griess assay
Accesso online:	https://doi.org/10.1007/s00726-025-03481-2
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