Markers for DNA damage are induced in the rat colon by the Alternaria toxin altertoxin-II, but not a complex extract of cultured Alternaria alternata

Mycotoxins produced by Alternaria spp. act genotoxic in cell-based studies, but data on their toxicity in vivo is scarce and urgently required for risk assessment. Thus, male Sprague-Dawley rats received single doses of a complex Alternaria toxin extract (CE; 50 mg/kg bw), altertoxin II (ATX-II; 0.2...

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Bibliografske podrobnosti

Principais autores:	Georg Aichinger, Gudrun Pahlke, Hannes Puntscher, Julia Groestlinger, Stephanie Grabher, Dominik Braun, Katharina Tillmann, Roberto Plasenzotti, Giorgia Del Favero, Benedikt Warth, Harald Höger, Doris Marko
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-10-01
Serija:	Frontiers in Toxicology
Teme:	genotoxicity in vivo emerging contaminant food safety mycotoxins natural toxicant
Online dostop:	https://www.frontiersin.org/articles/10.3389/ftox.2022.977147/full
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