Multiplex imaging of localized prostate tumors reveals altered spatial organization of AR-positive cells in the microenvironment

Summary: Mapping the spatial interactions of cancer, immune, and stromal cell states presents novel opportunities for patient stratification and for advancing immunotherapy. While single-cell studies revealed significant molecular heterogeneity in prostate cancer cells, the impact of spatial stromal...

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Detalhes bibliográficos

Principais autores:	Çiğdem Ak, Zeynep Sayar, Guillaume Thibault, Erik A. Burlingame, M.J. Kuykendall, Jennifer Eng, Alex Chitsazan, Koei Chin, Andrew C. Adey, Christopher Boniface, Paul T. Spellman, George V. Thomas, Ryan P. Kopp, Emek Demir, Young Hwan Chang, Vasilis Stavrinides, Sebnem Ece Eksi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-09-01
Colecção:	iScience
Assuntos:	Microenvironment Cancer Omics
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2589004224018935
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