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Predisposition to Alzheimer’s and Age-Related Brain Pathologies by PM2.5 Exposure: Perspective on the Roles of Oxidative Stress and TRPM2 Channel

Accumulating epidemiological evidence supports that chronic exposure to ambient fine particular matters of <2.5 μm (PM2.5) predisposes both children and adults to Alzheimer’s disease (AD) and age-related brain damage leading to dementia. There is also experimental evidence to show that PM2.5 expo...

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Principais autores: Lu Wang, Lin Yu Wei, Ran Ding, Yanyan Feng, Dongliang Li, Chaokun Li, Philippa Malko, Sharifah A. Syed Mortadza, Weidong Wu, Yaling Yin, Lin-Hua Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-02-01
coleção:Frontiers in Physiology
Assuntos:
Alzheimer’s disease
age-related brain pathologies
PM2.5
oxidative stress
TRPM2 channel
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphys.2020.00155/full
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