TDP-43 CSF Concentrations Increase Exponentially with Age in Metropolitan Mexico City Young Urbanites Highly Exposed to PM_2.5 and Ultrafine Particles and Historically Showing Alzheimer and Parkinson’s Hallmarks. Brain TDP-43 Pathology in MMC Residents Is Associated with High Cisternal CSF TDP-43 Concentrations

Environmental exposures to fine particulate matter (PM_2.5) and ultrafine particle matter (UFPM) are associated with overlapping Alzheimer’s, Parkinson’s and TAR DNA-binding protein 43 (TDP-43) hallmark protein pathologies in young Metropolitan Mexico City (MMC) urbanites. We measured CSF...

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主要な著者:	Lilian Calderón-Garcidueñas, Elijah W. Stommel, Ingolf Lachmann, Katharina Waniek, Chih-Kai Chao, Angélica González-Maciel, Edgar García-Rojas, Ricardo Torres-Jardón, Ricardo Delgado-Chávez, Partha S. Mukherjee
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2022-09-01
シリーズ:	Toxics
主題:	ALS air pollution Alzheimer’s Aβ1–42 α synuclein children
オンライン･アクセス:	https://www.mdpi.com/2305-6304/10/10/559
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